New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug
JR Crouse III - Coronary artery disease, 1996 - journals.lww.com
Niacin has been used for many years to treat hyperlipidemia. It has been shown to reduce
coronary death and non-fatal myocardial infarction and, in a separate analysis of long-term
(15-year) follow-up, all cause mortality. It reduces total cholesterol, low density lipoprotein
choelsterol (LDL-C) and triglycerides and increases high density lipoprotein cholesterol
(HDL-C). Sustained-release niacin may be associated with more dramatic changes in LDL-
C and triglyceride, whereas the short acting preparation causes greater increases in HDL-C …
coronary death and non-fatal myocardial infarction and, in a separate analysis of long-term
(15-year) follow-up, all cause mortality. It reduces total cholesterol, low density lipoprotein
choelsterol (LDL-C) and triglycerides and increases high density lipoprotein cholesterol
(HDL-C). Sustained-release niacin may be associated with more dramatic changes in LDL-
C and triglyceride, whereas the short acting preparation causes greater increases in HDL-C …