Serum potentially carries an archive of important histological information whose
determination could serve to improve early disease detection. The analysis of serum,
however, is analytically challenging due to the high dynamic concentration range of
constituent protein/peptide species, necessitating extensive fractionation prior to mass
spectrometric analyses. The low molecular weight (LMW) serum proteome is that
protein/peptide fraction from which high molecular weight proteins, such as albumin …