• The disciform response is characterized by its many manifestations determined by
subretinal neovascularization. Many advances have been made clinically and with
histopathologic correlation, but a clear understanding of the pathogenesis of subretinal
neovascularization has not yet been achieved at the basic level. The need to determine the
pathogenesis and understand the rationale for therapy argues strongly for the development
of a suitable experimental model of subretinal neovascularization. The macula is much more …