Use of the bovine model of tuberculosis for the development of improved vaccines and diagnostics

RG Hewinson, HM Vordermeier, BM Buddle - Tuberculosis, 2003 - Elsevier
Over the past few years there has been a resurgence in research into bovine tuberculosis
due to the sharp rise of the disease in countries such as Great Britain and to the continuing
problem of wild-life reservoirs in countries such as New Zealand. One of the goals of this
research is to develop cattle vaccines against TB. The initial testing of candidate vaccines is
carried out in laboratory animals, initially mice and subsequently guinea pigs. A unique
feature of the cattle vaccination programme is that candidate vaccines which show promise …