[HTML][HTML] Stem cells and cancer: two faces of eve

MF Clarke, M Fuller - Cell, 2006 - cell.com
MF Clarke, M Fuller
Cell, 2006cell.com
Recent evidence suggests that a subset of cancer cells within some tumors, the so-called
cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the
pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant
and normal stem cells may shed light on mechanisms that lead to cancer and suggest better
modes of treatment.
Recent evidence suggests that a subset of cancer cells within some tumors, the so-called cancer stem cells, may drive the growth and metastasis of these tumors. Understanding the pathways that regulate proliferation, self-renewal, survival, and differentiation of malignant and normal stem cells may shed light on mechanisms that lead to cancer and suggest better modes of treatment.
cell.com