[HTML][HTML] The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and …
W Li, DM Danilenko, S Bunting, R Ganesan… - Journal of biological …, 2009 - ASBMB
The trypsin-like serine protease marapsin is a member of the large protease gene cluster at
human chromosome 16p13. 3, which also contains the structurally related proteases testisin,
tryptase ε, tryptase γ, and EOS. To gain insight into the biological functions of marapsin, we
undertook a detailed gene expression analysis. It showed that marapsin expression was
restricted to tissues containing stratified squamous epithelia and was absent or only weakly
expressed in all other tissues, including the pancreas. Marapsin was constitutively …
human chromosome 16p13. 3, which also contains the structurally related proteases testisin,
tryptase ε, tryptase γ, and EOS. To gain insight into the biological functions of marapsin, we
undertook a detailed gene expression analysis. It showed that marapsin expression was
restricted to tissues containing stratified squamous epithelia and was absent or only weakly
expressed in all other tissues, including the pancreas. Marapsin was constitutively …