Pooling data from individual clinical trials in the COVID-19 era
E Petkova, EM Antman, AB Troxel - Jama, 2020 - jamanetwork.com
The rapid pace of the coronavirus disease 2019 (COVID-19) pandemic caused many
research efforts to be initiated quickly. In some cases, nationally based platform trials have
begun to report results. 1 More frequently, however, randomized clinical trials (RCTs) were
launched in local settings and in several cases missed the peak of the pandemic in their
region. Now, some individual studies are at risk of failing to meet recruitment targets
because of declining numbers of patients with COVID-19 who are being cared for at some …
research efforts to be initiated quickly. In some cases, nationally based platform trials have
begun to report results. 1 More frequently, however, randomized clinical trials (RCTs) were
launched in local settings and in several cases missed the peak of the pandemic in their
region. Now, some individual studies are at risk of failing to meet recruitment targets
because of declining numbers of patients with COVID-19 who are being cared for at some …
